The key to the treatment of drug-induced deafness is early detection and early treatment. In the process of using aminoglycoside antibiotics such as gentamicin, we need to monitor them. If we find signs of hearing loss, we need to use them early. Vitamin a 25000u, vitamin B, adenosine triphosphate, coenzyme A, cytochrome c, etc. all of these drugs are involved in the metabolism of cells. Vitamin A can promote the growth of neuroepithelium. Generally, after the above treatment, hearing can be kept stable and no longer Continue to decline.
There are many chances for infants to get sick. Sometimes the dosage of aminoglycoside antibiotics is too large. In addition, children are generally weak, so the chances of ototoxicosis are more than that of adults. When children are deaf, they will not tell themselves. Parents need to pay attention to early detection, give neurotrophic drugs as early as possible, and sometimes add hormone therapy. We found that after using the super dose of gentamicin, deafness occurred very quickly. After the rescue treatment, the hearing was completely recovered. For infants, more active treatment is needed. Because infants and young children are in the growing period, with vigorous development, strong vitality, and great hope for cure.
In the case of ototoxicosis caused by aminoglycoside antibiotics in conventional dosage, the hearing will be decreased gradually, and vitamin and neurotrophic drugs will be given for a long time, generally 3-6 months. After 6 months, the interval will be longer until the hearing is stable. For accumulated poisoning, only high-frequency hearing loss is common, and symptoms are mild. Some of them can recover after treatment. In clinical application, it is found that Chinese herbal medicine has certain curative effect, such as Rhizoma Polygonati, Atractylodis, Rhizoma Drynariae, Fructus Lycii, mulberry, astragalus, privet fruit, Salvia miltiorrhiza, etc.
In recent years, studies have found that the physiological function of the damaged cochlea may be restored. It is believed that the drugs can be excreted from the lymph of the inner ear and the channels on the cochlear cells. The SUBMICROSTRUCTURE of the cochlear hair cells can be repaired. The vascular stria has reversible changes, and the hair cells are expected to regenerate. In view of the findings of the above basic research, it shows a bright future for the treatment of drug-induced deafness.
For the deaf patients who are not effective in the treatment of drugs or whose hearing tends to be stable, we should actively improve their hearing and speech communication by means of hearing and speech rehabilitation measures. For children, it is necessary to avoid deafness and hoarseness.
At present, there are three kinds of rehabilitation measures with positive effects:
One is to choose the right hearing aid. Before selection, the hearing threshold and maximum comfort threshold corresponding to different sound frequencies of patients should be tested to determine the dynamic range of patients’ hearing. In the selection of hearing aids, we should pay attention to the functions of maximum output limit, automatic gain control or wide dynamic range compression, which can not only protect the existing hearing of patients, but also achieve better rehabilitation effect.
Second, cochlear implant. The average hearing threshold of speech frequency is often more than 90 decibels for the extremely deaf, and the effect of wearing hearing aids is poor. This is because the damage of inner ear sensory cells seriously hinders the transmission of auditory information. Although the amplified sound is natural and clear, the central auditory system of patients can not receive enough information. The cochlear implant is an electronic device that replaces the function of the human ear. It converts the received sound into encoded electrical signal, which is then transmitted to the transmission coil. The transmission coil transmits the signal to the subcutaneous receiving / stimulator through magnetic coupling. The receiving / stimulator decodes the signal and transmits it to the electrode implanted in the cochlea, so as to excite the auditory nerve fiber, transmit the sound information to the brain, and generate hearing Jue. Through cochlear implant, the hearing of patients can be improved to near normal level, thus laying a foundation for language learning.
The third is to improve the social communication ability of the deaf people who have no economic bearing capacity. The device can change the sound from the outside into vibration signal, which can be sensed by the patient through the skin. Through the device, the patient can not only feel the existence of environmental sound and respond, such as car sound, knocking, telephone sound, etc., but also improve the speech recognition ability by combining speech reading (lip reading). All of the above rehabilitation measures need hearing training and speech training to achieve the best effect of hearing speech rehabilitation.
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